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隱丹參酮

    
分析標準品,HPLC≥98%

Cryptotanshinone

源葉
B21586 一鍵復制產品信息
35825-57-1
C19H20O3
296.35
MFCD07636810
隱丹參醌
貨號 規格 價格 上海 北京 武漢 南京 購買數量
B21586-20mg
分析標準品,HPLC≥98% ¥150.00 >10 4 - 4
B21586-100mg
分析標準品,HPLC≥98% ¥472.00 >10 - - -
產品介紹 參考文獻(69篇) 質檢證書(COA) 摩爾濃度計算器 相關產品

產品介紹

藥理藥效:具有抗氧化、抗衰老功能,對治療冠心病、心絞痛、心肌損害有一定療效。隱丹參酮具有抑菌作用,1mg/ml對金黃色葡萄球菌及綠膿桿菌均有抑制作用,對溶血性鏈球菌亦有一定抑制作用。

熔點: 192°C(lit.)
沸點: 459 °C at 760 mmHg
比旋光度: -91.4 (CHCl3)
外觀: 橙紅色針狀結晶
溶解性: DMSO:3mg/ml
敏感性: 對光敏感
儲存條件: 2-8℃,避光
注意: 部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。

參考文獻(69篇)

64. [IF=5.7] Xue-Zhang et al."Discovery of Tetrahydro Tanshinone I as a Naturally Occurring Covalent Pan-Inhibitor Against Gut Microbial Bile Salt Hydrolases."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2024;XXXX(XXX):XXX-XXX 63. [IF=8.3] Ruiyan Zhu et al."Abscisic acid enhances SmAPK1-mediated phosphorylation of?SmbZIP4 to positively regulate tanshinone biosynthesis in Salvia miltiorrhiza."NEW PHYTOLOGIST.2024 Nov;: 62. [IF=8.1] Sheng Wang et al."Target-oriented rational design of composite bio-derived solvents for the green extraction of salvianolic acid B and tanshinones from Salvia miltiorrhiza root."SEPARATION AND PURIFICATION TECHNOLOGY.2025 Jun;359:130772 61. [IF=4.9] Yanbing Pan et al."Simultaneous detection of tanshinone I and cryptotanshinone using a carbon fiber microelectrode based on gold–palladium composite network."MICROCHEMICAL JOURNAL.2025 Mar;:113378 60. [IF=6.7] Mingzhu Qi et al."Qingxin Jieyu Granule alleviates myocardial infarction through inhibiting neutrophil extracellular traps via activating ANXA1/FPR2 axis."PHYTOMEDICINE.2024 Dec;135:156147 59. [IF=8.7] Zhe Li et al."Illuminating the fight against breast cancer: Preparation and visualized photothermal therapy of hyaluronic acid coated ZIF-8 loading with indocyanine green and cryptotanshinone for triple-negative breast cancer."Materials Today Bio.2024 Oct 58. [IF=6.2] Ying Ren et al."Effect of CeO2, TiO2 and SiO2 nanoparticles on the growth and quality of model medicinal plant Salvia miltiorrhiza by acting on soil microenvironment."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2024 Jul;280:116552 57. [IF=4.8] Qingquan Li et al."Identification of Senkyunolide I as a novel modulator of hepatic steatosis and PPARα signaling in zebrafish and hamster models."JOURNAL OF ETHNOPHARMACOLOGY.2025 Jan;336:118743 56. [IF=4.8] Zhengchao Ji et al."Holistic quality assessment and monitoring of YiXinShu capsule based on three-dimensional fingerprints combined with quantitative analysis, antioxidant activity and chemometrics."JOURNAL OF ETHNOPHARMACOLOGY.2024 Dec;335:118630 55. [IF=0.8] Cao Yezhi et al."Cryptotanshinone Inhibits the Proliferation of 5-Fluorouracil-Resistant Gastric Cancer SGC-7901/5-FU Cells Via the JAK2/STAT3 Pathway."PHARMACEUTICAL CHEMISTRY JOURNAL.2024 Jun;:1-10 54. [IF=2.6] Fan Yang et al."Preliminary Exploration of Potential Active Ingredients and Molecular Mechanisms of Yanggan Yishui Granules for Treating Hypertensive Nephropathy Using UPLC-Q-TOF/MS Coupled with Network Pharmacology and Molecular Docking Strategy."Journal 53. [IF=3.1] Miao Wang et al."Tanshinone IIA, originated from Salvia miltiorrhiza, activated EPO/EPOR-JAK2-STAT5 pathway in rat blood deficiency therapy."SOUTH AFRICAN JOURNAL OF BOTANY".2024 Jul;170:105 52. [IF=0.7] Shaomei Lin et al."Effect of Cryptotanshinone on BDNF/TrkB Pathway in Hippocampus of Chronic Stress-induced Depression Rats."Pharmacognosy Magazine.10.1177/09731296241236034 51. [IF=9.8] Ying Ren et al."Response of antioxidant activity, active constituent and rhizosphere microorganisms of Salvia miltiorrhiza to combined application of microbial inoculant, microalgae and biochar under Cu stress."SCIENCE OF THE TOTAL ENVIRONMENT".2024 May;9 50. [IF=1.1] Ji-Yong FU et al."Simultaneous determination of 19 constituents in the Jian-Nao-Ning mixture using high-performance liquid chromatography-tandem mass spectrometry."Separation Science Plus".2024 Feb;:2300222 49. [IF=5.4] Yingkun Sheng et al."Dan-shen Yin promotes bile acid metabolism and excretion to prevent atherosclerosis via activating FXR/BSEP signaling pathway."JOURNAL OF ETHNOPHARMACOLOGY".2024 Apr;:118209 48. [IF=3.8] Ying Zhang et al."Elucidating the distinctive regulatory effects and mechanisms of active compounds in Salvia miltiorrhiza Bunge via network pharmacology: Unveiling their roles in the modulation of platelet activation and thrombus formation."TOXICOLOGY AN 47. [IF=4.7] Xu Zhang et al."Rhein: A potent immunomodulator empowering largemouth bass against MSRV infection."FISH & SHELLFISH IMMUNOLOGY.2024 Jan;144:109284 46. [IF=5.4] Yi-Chao Liu et al."Mechanism of cryptotanshinone to improve endocrine and metabolic functions in the endometrium of PCOS rats."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;319:117346 45. [IF=1.8] Dimeng Song et al."Cryptotanshinone, a Potential SIRT3 Inhibitor, Suppresses Colorectal Cancer Proliferation in vitro and in vivo."Natural Product Communications.;(): 44. [IF=5.195] YiNi Gao et al."Jiedu-Quyu-Ziyin Fang (JQZF) inhibits the proliferation and activation of B cells in MRL/lpr mice via modulating the AKT/mTOR/c-Myc signaling pathway."JOURNAL OF ETHNOPHARMACOLOGY.2023 Oct;315:116625 43. [IF=6.449] Chaogeng Lyu et al."A field trials-based study reveals the effects of chlormequat chloride on the quality of medicinal plant Salvia miltiorrhiza Bge. (Lamiaceae) in practical cultivation."INDUSTRIAL CROPS AND PRODUCTS.2023 Apr;194:116396 42. [IF=6.208] Huan Zhao et al."Dihydrotanshinone I Inhibits the Lung Metastasis of Breast Cancer by Suppressing Neutrophil Extracellular Traps Formation."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(23):15180 41. [IF=1.496] Wenkai Wu et al."Cryptotanshinone From Salvia miltiorrhiza Inhibits the Growth of Tumors and Enhances the Efficacy of Chemotherapy in a Gastric Cancer Mouse Model."Natural Product Communications 40. [IF=5.988] Keke Guo et al."Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis."Frontiers in Pharmacology.2022; 13: 1036013 39. [IF=0] Danni Wang et al."Identification of Q-Markers from Hedan Tablet by employing “spider-web” mode and taking compounds’ hepatotoxicity into account."Chinese Herbal Medicines.2022 Aug;: 38. [IF=6.317] Ping Huang et al."Optimization of smashing tissue and ultrasonic extraction of tanshinones and their neuroprotective effect on cerebral ischemia/reperfusion injury by inhibiting parthanatos."Food & Function.2022 Aug;: 37. [IF=6.627] Jiadong Hu et al."Identification of Abietane-Type Diterpenoids and Phenolic Acids Biosynthesis Genes in Salvia apiana Jepson Through Full-Length Transcriptomic and Metabolomic Profiling."Frontiers in Plant Science.2022; 13: 919025 36. [IF=7.376] Chengtao Sun et al."Dihydrotanshinone I inhibits ovarian tumor growth by activating oxidative stress through Keap1-mediated Nrf2 ubiquitination degradation."Free Radical Bio Med. 2022 Feb;180:220 35. [IF=6.057] Qi Tong et al.Biosynthesis-based spatial metabolome of Salvia miltiorrhiza Bunge by combining metabolomics approaches with mass spectrometry-imaging.Talanta. 2021 Nov;:123045 34. [IF=2.971] Rubin Cheng et al."Cryptotanshinone enhances the efficacy of Bcr-Abl tyrosine kinase inhibitors via inhibiting STAT3 and eIF4E signalling pathways in chronic myeloid leukaemia."Pharm Biol. 2021;59(1):893-903 33. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 32. [IF=3.411] Liu Hongyan et al."Effect Study of Continuous Monoculture on the Quality of Salvia miltiorrhiza Bge Roots."Biomed Res Int. 2020;2020:4284385 31. [IF=3.51] Li-Ying Peng et al."Salvia miltiorrhiza Restrains Reactive Oxygen Species-Associated Pulmonary Fibrosis via Targeting Nrf2-Nox4 Redox Balance."Am J Chinese Med. 2019 Aug;47(05):1113-1131 30. [IF=3.69] Qian Zhang et al."Qishen Granule alleviates endoplasmic reticulum stress-induced myocardial apoptosis through IRE-1-CRYAB pathway in myocardial ischemia."J Ethnopharmacol. 2020 Apr;252:112573 29. [IF=4.411] Xiaoping Wang et al."Cryptotanshinone Ameliorates Doxorubicin-Induced Cardiotoxicity by Targeting Akt-GSK-3β-mPTP Pathway In Vitro."Molecules. 2021 Jan;26(5):1460 28. [IF=4.411] Yuanyuan Li et al."Quantitative Determination and Validation of Four Ketones in Salvia miltiorrhiza Bunge Using Quantitative Proton Nuclear Magnetic Resonance Spectroscopy."Molecules. 2020 Jan;25(9):2043 27. [IF=5.34] Tao-Fang Cheng et al."Compound Dan Zhi tablet attenuates experimental ischemic stroke via inhibiting platelet activation and thrombus formation."Phytomedicine. 2020 Dec;79:153330 26. [IF=6.475] Shi Qiu et al."Selection of appropriate post-harvest processing methods based on the metabolomics analysis of Salvia miltiorrhiza Bunge."Food Res Int. 2021 Jun;144:110366 25. [IF=7.514] Tong Wang et al."A hydrophobic deep eutectic solvents-based integrated method for efficient and green extraction and recovery of natural products from Rosmarinus officinalis leaves, Ginkgo biloba leaves and Salvia miltiorrhiza roots."Food Chem. 2021 Nov;3 24. [IF=3.361] Taofang Cheng et al."Hybrid multidimensional data acquisition and data processing strategy for comprehensive characterization of known, unknown and isomeric compounds from the compound Dan Zhi Tablet by UPLC-TWIMS-QTOFMS."Rsc Adv. 2019 Mar;9(16):8714-8727 23. [IF=3.414] Yu-xiang Fei et al."Salvia miltiorrhiza Bunge (Danshen) extract attenuates permanent cerebral ischemia through inhibiting platelet activation in rats."J Ethnopharmacol. 2017 Jul;207:57 22. [IF=3.935] Nan Mi et al."Metabolite profiling of traditional Chinese medicine formula Dan Zhi Tablet: An integrated strategy based on UPLC-QTOF/MS combined with multivariate statistical analysis."J Pharmaceut Biomed. 2019 Feb;164:70 21. [IF=5.64] Wu Dousheng et al."Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum."Front Microbiol. 2015 Dec;0:1466 20. [IF=7.514] Tiehua Zhang et al."In vitro and in silico perspectives on estrogenicity of tanshinones from Salvia miltiorrhiza."Food Chem. 2019 Jan;270:281 19. Xia, Yanqiu, et al. "Cryptotanshinone reverses reproductive disturbances in rats with dehydroepiandrosterone-induced polycystic ovary syndrome." American journal of translational research 9.5 (2017): 2447. 18. 李曉婷,決利利,郝海軍,王世廣.隱丹參酮納米混懸劑的制備及其抗腫瘤活性[J].中成藥,2021,43(01):6-10. 17. 馬麗娟,王錫恩,劉培,陳蜜,張靜,彭敏.隱丹參酮調控Wnt/β-catenin信號通路對胃癌細胞抑制作用的研究[J].新中醫,2020,52(21):1-5. 16. 陳天朝,耿夢麗,馬彥江,李沁,姚超,程思卿,王嬌.丹參不同炮制品飲片與標準湯劑的物性參數及化學成分相關性[J].中成藥,2021,43(03):824-829 15. 趙志國, 段文娟, 張曉夢,等. HPLC-DAD-ESI-TOF/MS鑒別和測定前列欣膠囊中多種成分及其多指標定量指紋圖譜研究[J]. 藥物分析雜志, 2017, 037(010):1810-1816. 14. 李清清 張繼芬. 冠心寧中14種成分的含量測定[J]. 蘇鹽科技 2019 046(006):33-35. 13. 王蕓, 陳軍峰, 張磊,等. 基于"有效成分-性狀"的關聯分析評價丹參品質的研究[J]. 世界科學技術:中醫藥現代化, 2019(5):835-843. 12. 崔偉亮. 丹參酒炙前后HPLC指紋圖譜色譜峰歸屬比較[J]. 遼寧中醫雜志, v.46;No.507(08):1707-1709. 11. 敏敏 趙志國 劉偉 等. HPLC-DAD法同時測定三種來源丹參飲片中水溶性和脂溶性成分[J]. 山東科學 2019(6). 10. 石蔚華 趙筱萍 陳曉玲.三葉糖脂清DPP-4抑制成分篩選及其調控JNK/AKT信號通路改善胰島素抵抗的機制研究[J].浙江中醫藥大學學報 2019 43(01):7-13. 9. 閆妍 石磊 史寧 郭宏舉 耿帥 溫彬宇.UPLC-Q-TOF-MS同時測定天王補心片中丹參的主要成分[J].解放軍藥學學報 2018 34(01):55-57. 8. 孫錦 林力 彭勍 等. 不同濃度乙醇提取丹參中12種成分比較研究[J]. 中國中醫藥信息雜志 2019(9). 7. 郝海軍, 屈戰果, 范明松. 隱丹參酮納米結構脂質載體的制備及藥動學研究[J]. 中成藥, 2020, 042(004):831-835. 6. 鄧鳳春, 于占江, 楊鈺,等. 隱丹參酮對人胃癌細胞SGC-7901凋亡的影響及其機制[J]. 北京中醫藥大學學報, 2015. 5. 鄧鳳春, 楊鈺, 趙紅曄,等. 隱丹參酮抑制人胃癌SGC-7901細胞增殖的實驗研究[J]. 中外醫療, 2014(35):49-50. 4. 彭國文,柳超,時曉靜,郝海軍.隱丹參酮固體脂質納米粒的制備及藥動學研究[J].中藥材,2019,42(03):626-629. 3. 何家杰,李敏,唐國富,李厚澤,綦曉龍.異隱丹參酮對胃癌細胞增殖、周期和凋亡的影響[J].臨床腫瘤學雜志,2019,24(02):129-132. 2. 張玉, 戚瑩雪, 王蕾,等. 山東丹參脂溶性成分的地域分布特點研究[J]. 中藥材, 2018, 041(011):2522-2526. 1. 張芮乾,吳曉毅,胡添源,宋雅迪,高偉,黃璐琦.基于丹參酮類化合物生源途徑的丹參質量標志物研究思路探討[J].中國中藥雜志,2020,45(13):3098-3103.

質檢證書(COA)

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批號:JS298415 貨號:S20001-25g
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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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