貨號	規(guī)格	價格	上海	北京	武漢	南京
S87463-1mg	99.8%	￥220.00 S87463-1mg ￥220.00 現(xiàn)貨	5 5	-	-	-
S87463-2mg	99.8%	￥300.00 S87463-2mg ￥300.00 現(xiàn)貨	5 5	-	-	-
S87463-5mg	99.8%	￥370.00 S87463-5mg ￥370.00 現(xiàn)貨	7 7	-	-	-
S87463-10mg	99.8%	￥720.00 S87463-10mg ￥720.00 現(xiàn)貨	5 5	-	-	-
S87463-25mg	99.8%	￥760.00 S87463-25mg ￥760.00 現(xiàn)貨	4 4	-	-	-
S87463-50mg	≥99%	￥1390.00 S87463-50mg ￥1390.00 2-3天	0 貨期：2-3天	-	-	-

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產(chǎn)品介紹

Acebilustat (CTX-4430) is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory agent.

產(chǎn)品描述：

Acebilustat (CTX-4430) is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory agent.

靶點：

Aminopeptidase;Aminopeptidase;?LTR

體外研究：

Acebilustat (CTX-4430) is a leukotriene A4 hydrolase inhibitor, which is safe and well tolerated in phase 1 trial. Acebilustat is an antiinflammatory drug in development for the treatment of CF and other diseases. It is a potent inhibitor of the enzyme leukotriene A4 hydrolase (LTA4H), which catalyzes the rate-limiting step in the formation of leukotriene B4 (LTB4), a potent chemoattractant and activator of inflammatory immune cells including neutrophils

參考文獻：

1. Elborn JS, et al. Phase 1 Studies of Acebilustat: Biomarker Response and Safety in Patients with Cystic Fibrosis. Clin Transl Sci. 2016 Nov 2 2. Elborn JS, et al. Phase I Studies of Acebilustat: Pharmacokinetics, Pharmacodynamics, Food Effect, and CYP3A Induction. Clin Transl Sci. 2016 Oct 28.

溶解性：

Soluble in DMSO

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	2.077 ml	10.383 ml	20.767 ml
5 mM	0.415 ml	2.077 ml	4.153 ml
10 mM	0.208 ml	1.038 ml	2.077 ml
50 mM	0.042 ml	0.208 ml	0.415 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻

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