貨號	規(guī)格	價格	上海	北京	武漢	南京	購買數(shù)量
S86217-50mg	99.4%	￥240.00 S86217-50mg ￥240.00 現(xiàn)貨	17 >10	-	-	-
S86217-100mg	99.4%	￥400.00 S86217-100mg ￥400.00 現(xiàn)貨	6 6	-	-	-

產(chǎn)品介紹

Piroctone olamine is a pyridine derivate. It is known to have a fungicidal effect.

產(chǎn)品描述：

Piroctone olamine is a pyridine derivate. It is known to have a fungicidal effect.

靶點：

Antifungal;Antibiotic;Antifungal

體內(nèi)研究：

This work aimed to evaluate the antifungal activity of Piroctone olamine in the treatment of intra-abdominal candidiasis in an experimental model using Swiss mice. The treatment with Piroctone olamine (0.5 mg/kg) is performed 72 h after infection by intraperitoneal administration. For comparison, a group of animals (n=6) is treated with Amphotericin B (0.5 mg/kg). The mycological diagnosis is made by collecting the liver, spleen and kidneys. Data regarding the fungal growth and mortality are analyzed statistically by Student’s t test and analysis of variance, with level of significance set at P<0.05. The difference in fungal growth scoring between the control group and the treatment groups (Piroctone olamine and Amphotericin B) is statistically significant (P<0.05)

參考文獻：

1. Youn HJ, et al. Efficacy and Safety of Cream Containing Climbazole/Piroctone Olamine for Facial Seborrheic Dermatitis: A Single-Center, Open-Label Split-Face Clinical Study. Ann Dermatol. 2016 Dec;28(6):733-739. 2. do Couto FM, et al. Antifungal activity of the piroctone olamine in experimental intra-abdominal candidiasis. Springerplus. 2016 Apr 16;5:468.

溶解性：

Soluble in DMSO、H2O

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	3.351 ml	16.755 ml	33.51 ml
5 mM	0.67 ml	3.351 ml	6.702 ml
10 mM	0.335 ml	1.675 ml	3.351 ml
50 mM	0.067 ml	0.335 ml	0.67 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻

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