貨號	規格	價格	上海	北京	武漢	南京
S85532-2mg	99.1%	￥204.00 S85532-2mg ￥204.00 現貨	5 5	-	-	-
S85532-5mg	99.1%	￥367.20 S85532-5mg ￥367.20 現貨	6 6	-	-	-
S85532-10mg	99.1%	￥557.60 S85532-10mg ￥557.60 現貨	4 4	-	-	-
S85532-25mg	99.1%	￥1224.00 S85532-25mg ￥1224.00 現貨	6 6	-	-	-
S85532-50mg	99.1%	￥1860.00 S85532-50mg ￥1860.00 現貨	5 5	-	-	-
S85532-100mg	≥99%	￥2750.00 S85532-100mg ￥2750.00 2-3天	0 貨期：2-3天	-	-	-

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產品介紹

ML213 is a selective activator of Kv7.2 and Kv7.4 channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.

產品描述：

ML213 is a selective activator of Kv7.2 and Kv7.4 channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.

靶點：

EC50: 230 nM (Kv7.2 channel), 510 nM (Kv7.4 channel);PotassiumChannel

參考文獻：

1. Brueggemann LI, et al. Differential activation of vascular smooth muscle Kv7.4, Kv7.5, and Kv7.4/7.5 channels by ML213 and ICA-069673. Mol Pharmacol. 2014 Sep;86(3):330-41. 2. Jepps TA, et al. Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370. Br J Pharmacol. 2014 Oct;171(19):4413-24. 3. Yu H, et al. Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener. ACS Chem Neurosci. 2011 Oct 19;2(10):572-577

溶解性：

Soluble in DMSO

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	3.885 ml	19.427 ml	38.855 ml
5 mM	0.777 ml	3.885 ml	7.771 ml
10 mM	0.389 ml	1.943 ml	3.885 ml
50 mM	0.078 ml	0.389 ml	0.777 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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ML-213