| 產品描述： | Dilmapimod (SB-681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease. |
| 靶點： |
p38 MAPK;Autophagy;p38MAPK;Autophagy |
| 體外研究： |
Dilmapimod (SB-681323) potently inhibits p38 MAPK signaling, measured by inhibition of sorbitol-induced pHSP27 expression |
| 參考文獻： |
1. Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50(1):94-100. |
| 溶解性： |
Soluble in DMSO |
| 保存條件： |
-20℃ |
| 配置溶液濃度參考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.191 ml |
10.955 ml |
21.91 ml |
| 5 mM |
0.438 ml |
2.191 ml |
4.382 ml |
| 10 mM |
0.219 ml |
1.095 ml |
2.191 ml |
| 50 mM |
0.044 ml |
0.219 ml |
0.438 ml |
|
| 注意： |
部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。 |
上海工商
危險品化學品經營許可證（不帶存儲）
營業執照(三證合一)
北京