貨號	規格	價格	上海	北京	武漢	南京	購買數量
S85170-100mg	99.4%	￥700.00 S85170-100mg ￥700.00 現貨	6 6	-	-	-
S85170-250mg	≥99%	￥1700.00 S85170-250mg ￥1700.00 2-3天	0 貨期：2-3天	-	-	-

產品介紹

Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency

產品描述：

靶點：

Bacterial;SARS-CoV;Antibiotic;Antibacterial;Antibiotic

體內研究：

Clofoctol (175 mg/kg; i.p.; daily for 37 days) is capable of blocking tumour growth without apparent toxicity in a mouse model of human prostate cancer xenograft. Clofoctol (62.5 mg/kg; i.p.; twice) inhibits SARS-CoV-2 replication and lowers inflammation in lungs in mice with SARS-CoV-2 infection Animal Model: Male athymic nude mice (BALB/c, nu/nu-NCr) aged 4–6 weeks, human prostate cancer xenograft model Dosage: 175 mg/kg Administration: Intraperitoneal injection, daily for 37 days Result: Significantly inhibited PC3 tumour growth, tumour weight was also reduced by 60%.

參考文獻：

1. Ghilardi PL, et al. Treatment of ear, nose and throat infections with clofoctol. Drugs Exp Clin Res. 1985;11(11):815-8. 2. Wang M, et al. Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer. Br J Pharmacol. 2014 Oct;171(19):4478-89. 3. Belouzard S, et al. Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice. PLoS Pathog. 2022 May 19;18(5):e1010498.

溶解性：

Soluble in DMSO

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	2.737 ml	13.686 ml	27.372 ml
5 mM	0.547 ml	2.737 ml	5.474 ml
10 mM	0.274 ml	1.369 ml	2.737 ml
50 mM	0.055 ml	0.274 ml	0.547 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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CLOFOCTOL