品牌	貨號(hào)	產(chǎn)品規(guī)格	價(jià)格(RMB)	庫(kù)存（上海）	北京	武漢	南京	購(gòu)買數(shù)量
源葉(MedMol)	S84832-50mg	98%	￥520.00元	2	-	-	-
源葉(MedMol)	S84832-250mg	98%	￥1480.00元	預(yù)計(jì)交期：2-3天	-	-	-

產(chǎn)品介紹

Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. Antioxidant

產(chǎn)品描述： Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. Antioxidant

靶點(diǎn)： Human Endogenous Metabolite;Chloridechannel;EndogenousMetabolite

體內(nèi)研究：
Hypotaurine has antinociceptive effects on thermal, mechanical, and chemical nociception in the spinal cord. In CCI rats, hypotaurine alleviates mechanical allodynia and thermal hyperalgesia. Intrathecal hypotaurine suppresses acute, inflammatory, and neuropathic pain. Hypotaurine may regulate nociceptive transmission physiologically by activating glycinergic neurons in the spinal cord

參考文獻(xiàn)：
1. Green TR, et al. Antioxidant role and subcellular location of hypotaurine and taurine in human neutrophils. Biochim Biophys Acta. 1991 Jan 23;1073(1):91-7. https://www.ncbi.nlm.nih.gov/pubmed/1846756 2. Gao P, et al. Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling. Oncotarget. 2016 Mar 22;7(12):15200-14. 3. Hara K, et al. Antinociceptive effect of intrathecal administration of hypotaurine in rat models of inflammatory and neuropathic pain. Amino Acids. 2012 Jul;43(1):397-404. Hara K, et al. Antinociceptive effect of intrathecal administration of hypotaurine

溶解性： Soluble in H2O

保存條件： -20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	9.162 ml	45.809 ml	91.617 ml
5 mM	1.832 ml	9.162 ml	18.323 ml
10 mM	0.916 ml	4.581 ml	9.162 ml
50 mM	0.183 ml	0.916 ml	1.832 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)

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