產(chǎn)品描述: | Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity |
靶點(diǎn): |
Parasite;Antibiotic;?Parasite |
體內(nèi)研究: |
Oxyclozanide (15 mg/kg (羊),10 mg/kg (牛);口服) 在羊和牛中顯示出抗寄生蟲的效果。 Oxyclozanide (1500-5000 mg/kg;口服,一次) 在大鼠急性毒性試驗(yàn)中出現(xiàn)多種中毒癥狀 |
參考文獻(xiàn): |
1. Georgiev B, Gruev A. Efektivnost na levamizole i oxyclozanide sreshtu paramfistomatozata po ovtsete i govedata [Effectiveness of levamisole and oxyclozanide in paramphistomiasis in sheep and cattle]. Vet Med Nauki. 1979;16(3):45-51. 2. Wang W, et al. Acute and Subacute Toxicity Assessment of Oxyclozanide in Wistar Rats. Front Vet Sci. 2019 Sep 6;6:294. 3. Levinson MR, et al. The in vitro antibacterial activity of the anthelmintic drug oxyclozanide against common small animal bacterial pathogens. Vet Dermatol. 2019 Aug;30(4):314-e87. |
溶解性: |
DMSO : 100 mg/mL (249.09 mM; Need ultrasonic) |
保存條件: |
2-8℃ |
配置溶液濃度參考: |
|
1mg |
5mg |
10mg |
1 mM |
2.491 ml |
12.455 ml |
24.909 ml |
5 mM |
0.498 ml |
2.491 ml |
4.982 ml |
10 mM |
0.249 ml |
1.245 ml |
2.491 ml |
50 mM |
0.05 ml |
0.249 ml |
0.498 ml |
|
注意: |
部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。 |