貨號	規格	價格	上海	北京	武漢	南京
S84251-1mg	99.8%	￥385.00 S84251-1mg ￥385.00 現貨	9 9	-	-	-
S84251-5mg	99.8%	￥890.00 S84251-5mg ￥890.00 現貨	7 7	-	-	-
S84251-25mg	99.8%	￥2350.00 S84251-25mg ￥2350.00 現貨	6 6	-	-	-

產品介紹

Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment

產品描述：

靶點：

Gap Junction Protein;GapJunctionProtein

體內研究：

Gap 27 (300 μM) inhibits relaxation by 40% in thoracic aorta and the superior mesenteric artery. Gap 27 also attenuates the endothelium-dependent component of the relaxation induced by ATP in thoracic aorta.

參考文獻：

1. Ilvesaro J, et al. Connexin-mimetic peptide Gap 27 decreases osteoclastic activity. BMC Musculoskelet Disord. 2001;2:10. 2. Edwards G, et al. Role of gap junctions in the responses to EDHF in rat and guinea-pig small arteries. Br J Pharmacol. 1999 Dec;128(8):1788-94. 3. Chaytor AT,e t al. Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries. J Physiol. 1998 Apr 15;508 ( Pt 2):561-73.

溶解性：

Soluble in H2O

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	0.767 ml	3.833 ml	7.666 ml
5 mM	0.153 ml	0.767 ml	1.533 ml
10 mM	0.077 ml	0.383 ml	0.767 ml
50 mM	0.015 ml	0.077 ml	0.153 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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濃度

體積

分子摩爾量

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GAP 27