貨號	規格	價格	上海	北京	武漢	南京
S84223-5mg	98.3%	￥170.00 S84223-5mg ￥170.00 現貨	9 9	-	-	-
S84223-10mg	98.3%	￥250.00 S84223-10mg ￥250.00 現貨	9 9	-	-	-
S84223-50mg	98.3%	￥590.00 S84223-50mg ￥590.00 現貨	7 7	-	-	-
S84223-100mg	98.3%	￥940.00 S84223-100mg ￥940.00 現貨	4 4	-	-	-

產品介紹

Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist

產品描述：

Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist

靶點：

Androgen Receptor;AndrogenReceptor

體內研究：

Clascoterone is a new potent topical antiandrogen potentially useful in acne vulgaris. Clascoterone 1% cream was very well tolerated, and was significantly better than placebo regarding TLC (P = 0·0017), ILC (P = 0·0134) and ASI (P = 0·0090), and also clinically more effective than comparator. The product also induced a faster attainment of 50% improvement in all the above parameters.

參考文獻：

1. Trifu V, et al. Cortexolone 17α-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0·05% cream. Br J Dermatol. 2011 Jul;165(1):177-83. 2. Celasco G, et al. Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist. Arzneimittelforschung. 2004;54(12):881-6.

溶解性：

Soluble in DMSO

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	2.484 ml	12.422 ml	24.843 ml
5 mM	0.497 ml	2.484 ml	4.969 ml
10 mM	0.248 ml	1.242 ml	2.484 ml
50 mM	0.05 ml	0.248 ml	0.497 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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濃度

體積

分子摩爾量

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