貨號	規格	價格	上海	北京	武漢	南京	購買數量
S83962-100mg	98.5%	￥480.00 S83962-100mg ￥480.00 現貨	7 7	-	-	-

產品介紹

L-DABA (L-2,4-Diaminobutyric acid) is a week GABA transaminase inhibitor with an IC50 of larger than 500 μM; exhibits antitumor activity in vivo and in vitro.

產品描述：

L-DABA (L-2,4-Diaminobutyric acid) is a week GABA transaminase inhibitor with an IC50 of larger than 500 μM; exhibits antitumor activity in vivo and in vitro.

靶點：

Human Endogenous Metabolite;GABAReceptor;?EndogenousMetabolite

體內研究：

Treatment with L-DABA results in 43.4% reduction of tumor growth. L-DABA is a more effective inhibitor of GABA transaminase in vivo than in vitro

參考文獻：

1. Ronquist G, et al. Antitumor activity of L-2,4 diaminobuturic acid against mouse fibrosarcoma cells in vitro and in vivo. J Cancer Res Clin Oncol. 1980;96(3):259-68. 2. Beart PM, et al. l-2,4-Diaminobutyric acid and the GABA system. Neurosci Lett. 1977 Jul;5(3-4):193-8. 3. Panasci L, et al. The cytolytic effect of L-2,4 diaminobutyric acid with malignant glioma cells and fibroblasts. Cancer Chemother Pharmacol. 1988;21(2):143-4.

溶解性：

H2O : 1 mg/mL (8.47 mM; Need ultrasonic)

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	5.024 ml	25.12 ml	50.24 ml
5 mM	1.005 ml	5.024 ml	10.048 ml
10 mM	0.502 ml	2.512 ml	5.024 ml
50 mM	0.1 ml	0.502 ml	1.005 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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L-DAB HBR