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Tetrahydrobiopterin

    98%

Tetrahydrobiopterin

源葉(MedMol)
S83956
17528-72-2
C9H15N5O3
241.25
四氫生物喋呤;5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1h)-pteridinon;5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1h)-pteridinone;bh4;TETRAHYDRO-L-BIOPTERIN, DIHYDROCHLORIDE;THB, 2HCL;6R
品牌 貨號 產品規格 價格(RMB) 庫存(上海) 北京 武漢 南京 購買數量
源葉(MedMol) S83956-5mg 98% ¥1100.00元 5 - - -
源葉(MedMol) S83956-10mg 98% ¥1900.00元 7 - - -
源葉(MedMol) S83956-50mg 98% ¥6700.00元 6 - - -
產品介紹 參考文獻(3篇) 質檢證書(COA) 摩爾濃度計算器 相關產品

產品介紹

Tetrahydrobiopterin ((Rac)-Sapropterin) is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.

產品描述:

Tetrahydrobiopterin ((Rac)-Sapropterin) is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.

靶點: Human Endogenous Metabolite;NOS;?EndogenousMetabolite
體內研究: To assess the levels of Tetrahydrobiopterin in the retina, three to five pools of retinas are collected from WT and hph-1mice at postnatal age 7, 14, and 22 and evaluated by LC-MS/MS. LC-MS/MS analysis confirm a significant decrease by approximately 90% in the concentration levels of Tetrahydrobiopterin in retinal tissue from hph-1 mice (0.0009±0.0006; p<0.0001, 0.01±0.001; p<0.0001 and 2.45±0.40; p<0.005) compare to the WT group (0.014±0.001, 0.092±0.01, and 23.13±6.44) at P7, P14, and P22, respectively
參考文獻: 1. Rivera JC, et al. Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina. J Neuroinflammation. 2017 Sep 6;14(1):181.
溶解性: DMSO  :  50  mg/mL  (207.25  mM;  Need  ultrasonic)
保存條件: -20℃
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 4.145 ml 20.725 ml 41.451 ml
5 mM 0.829 ml 4.145 ml 8.29 ml
10 mM 0.415 ml 2.073 ml 4.145 ml
50 mM 0.083 ml 0.415 ml 0.829 ml
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質檢證書(COA)

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批號:JS298415 貨號:S20001-25g
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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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