貨號	規格	價格	上海	北京	武漢	南京
S83267-5mg	99.9%	￥800.00 S83267-5mg ￥800.00 現貨	8 8	-	-	-
S83267-10mg	99.9%	￥1500.00 S83267-10mg ￥1500.00 現貨	6 6	-	-	-
S83267-50mg	99.9%	￥4500.00 S83267-50mg ￥4500.00 現貨	3 3	-	-	-
S83267-100mg	≥98%	￥6870.00 S83267-100mg ￥6870.00 2-3天	0 貨期：2-3天	-	-	-

產品介紹

CB1-IN-1 (BPRCB1184) is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. IC50 value: 0.3 nM (Ki, CB1R) 21 nM (Ki, CB2R) Target: CB1R in vivo: CB1-IN-1 is a novel peripherally restricted cannabinoid 1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice. CB1-IN-1 has great potential to ameliorate this related metabolic syndrome.

產品描述：

靶點：

Cannabinoid Receptor;CannabinoidReceptor

參考文獻：

1. Chang CP, et al. Discovery of 1-(2,4-dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5-(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice. J Med Chem. 2013 Dec 27;56(24):9920-33.

溶解性：

Soluble in DMSO

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	1.33 ml	6.652 ml	13.304 ml
5 mM	0.266 ml	1.33 ml	2.661 ml
10 mM	0.133 ml	0.665 ml	1.33 ml
50 mM	0.027 ml	0.133 ml	0.266 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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