產(chǎn)品描述: | RI-2 is a reversible RAD51 inhibitor, with an IC50 of 44.17 μM, and specifically inhibits homologous recombination repair in human cells. |
靶點: |
IC50: 44.17 μM (RAD51);DNA/RNASynthesis |
體外研究: |
RI-2 (7a) is a reversible RAD51 inhibitor, with an IC50 of 44.17 μM. RI-2 specifically inhibits homologous recombination repair in human cells. RI-2 (150 μM) induces a significant sensitization of cells |
參考文獻: |
1. Budke B, et al. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. J Med Chem. 2013 Jan 10;56(1):254-63. |
溶解性: |
soluble in DMSO |
保存條件: |
-20℃ |
配置溶液濃度參考: |
|
1mg |
5mg |
10mg |
1 mM |
2.308 ml |
11.54 ml |
23.08 ml |
5 mM |
0.462 ml |
2.308 ml |
4.616 ml |
10 mM |
0.231 ml |
1.154 ml |
2.308 ml |
50 mM |
0.046 ml |
0.231 ml |
0.462 ml |
|
注意: |
部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。 |