貨號	規格	價格	上海	北京	武漢	南京	購買數量
S82789-5mg	≥98%	￥4200.00 S82789-5mg ￥4200.00 2-3天	0 貨期：2-3天	-	-	-
S82789-10mg	≥98%	￥6600.00 S82789-10mg ￥6600.00 2-3天	0 貨期：2-3天	-	-	-

產品介紹

VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.

產品描述：

VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.

靶點：

Cysteine Protease;CysteineProtease

體外研究：

VBY-825 is a potent assayed cathepsins inhibitor and its potency against at least one cathepsin, cathepsin S, extends across species relevant for pharmacology studies, specifically mouse. 10 mg/kg/day dose of VBY-825 achieves a trough plasma concentration >200nM, which is well above that required for full inhibition of the intracellular activity of cathepsins B, F, K, L, S and V in both mouse and human cell lines.

參考文獻：

1. Elie BT, et al. Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model. Biochimie. 2010 Nov;92(11):1618-24.

溶解性：

soluble in DMSO

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	1.867 ml	9.336 ml	18.672 ml
5 mM	0.373 ml	1.867 ml	3.734 ml
10 mM	0.187 ml	0.934 ml	1.867 ml
50 mM	0.037 ml	0.187 ml	0.373 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

質檢證書(COA)

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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

質量

濃度

體積

分子摩爾量

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