貨號	規格	價格	上海	北京	武漢	南京	購買數量
S82439-50mg	≥99%	￥550.00 S82439-50mg ￥550.00 2-3天	0 貨期：2-3天	-	-	-

產品介紹

Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect.

產品描述：

靶點：

Cholinesterase (ChE);5-HTReceptor;?AChE

體內研究：

Protriptyline hydrochloride (10 mg/kg; i.p.; for 21 days; rat model of AD) improves spatial learning and retention memory in STZ treated rats

參考文獻：

1. Bansode SB, et, al. Molecular investigations of protriptyline as a multi-target directed ligand in Alzheimer's disease. PLoS One. 2014 Aug 20;9(8):e105196. 2. Chang HT, et, al. The mechanism of protriptyline-induced Ca2+ movement and non-Ca2+-triggered cell death in PC3 human prostate cancer cells. J Recept Signal Transduct Res. 2015;35(5):429-34. 3. Tiwari V, et, al. Protriptyline improves spatial memory and reduces oxidative damage by regulating NFκB-BDNF/CREB signaling axis in streptozotocin-induced rat model of Alzheimer's disease. Brain Res. 2021 Mar 1;1754:147261.

溶解性：

Soluble in H2O、DMSO

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	3.335 ml	16.676 ml	33.351 ml
5 mM	0.667 ml	3.335 ml	6.67 ml
10 mM	0.334 ml	1.668 ml	3.335 ml
50 mM	0.067 ml	0.334 ml	0.667 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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分子摩爾量

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PROTRIPTYLINE HYDROCHLORIDE