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Suplatast Tosilate

    
99.6%

Suplatast Tosilate

源葉(MedMol)
S81571 一鍵復(fù)制產(chǎn)品信息
94055-76-2
C23H33NO7S2
499.64
甲磺司特;(2-(4-(3-乙氧基-2-羥基丙氧基)苯基氨基甲酰)乙基)二甲基锍對甲苯磺酸鹽;(2-(4-(3-Ethoxy-2-hydroxypropoxy)phenylcarbamoyl)ethyl)dimethylsulfonium p-toluenesulfonate;(3-(4-(3-ethoxy-2-hydroxypropoxy)phenylamino)-3-oxopropyl)dim
貨號(hào) 規(guī)格 價(jià)格 上海 北京 武漢 南京 購買數(shù)量
S81571-100mg
99.6% ¥240.00 >10 - - -
S81571-500mg
99.6% ¥780.00 >10 - - -
S81571-1g
99.6% ¥1180.00 >10 - - -
產(chǎn)品介紹 參考文獻(xiàn) 質(zhì)檢證書(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis. Suplatast Tosilate is an anti-allergic agent. Suplatast Tosilate has antiasthmatic, anti-inflammatory and antifibrotic activity

產(chǎn)品描述:

Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis. Suplatast Tosilate is an anti-allergic agent. Suplatast Tosilate has antiasthmatic, anti-inflammatory and antifibrotic activity

靶點(diǎn): IL-2;IL-5;IL-13;ILReceptor;?Interleukin
體內(nèi)研究: Suplatast Tosilate (100 mg/kg; once daily for 21 d) inhibits the production of Th2 cytokines, which inhibits eosinophil infiltration into the murine airway, IgE synthesis, and development of BHR, in a murine model of asthma. Suplatast Tosilate (100 μg/kg; once daily for 14 d) strongly suppresses immunoglobulin E contents in serum
參考文獻(xiàn): 1. Yanagihara Y, et, al. Suppression of IgE production by IPD-1151T (suplatast tosilate), a new dimethylsulfonium agent: (2). Regulation of human IgE response. Jpn J Pharmacol. 1993 Jan;61(1):31-9. 2. Zhao GD, et, al. Effect of suplatast tosilate (IPD-1151T) on a mouse model of asthma: inhibition of eosinophilic inflammation and bronchial hyperresponsiveness. Int Arch Allergy Immunol. 2000 Feb;121(2):116-22. 3. Kurokawa M, et, al. Suppressive effects of anti-allergic agent suplatast tosilate (IPD-1151T) on the expression of co-stimulatory molecules on mouse splenocytes in vivo. Mediators Inflamm. 2001 Dec;10(6):333-7. 4. Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N. Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice. J Pharmacol Exp Ther. 2009 Jan;328(1):55-61.
溶解性: Soluble  in  DMSO、H2O
保存條件: RT
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 2.001 ml 10.007 ml 20.014 ml
5 mM 0.4 ml 2.001 ml 4.003 ml
10 mM 0.2 ml 1.001 ml 2.001 ml
50 mM 0.04 ml 0.2 ml 0.4 ml
注意: 部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。

參考文獻(xiàn)

質(zhì)檢證書(COA)

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批號(hào):JS298415 貨號(hào):S20001-25g
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摩爾濃度計(jì)算器

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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