品牌：源葉(MedMol)

產品編號：S81439 一鍵復制產品信息

CAS號：236395-14-5

分子式：C₁₇H₁₆N₂O₃

分子量：296.324

別名：艾司利卡西平醋酸鹽; 艾司利卡西平醋酸酯; (S)-(-)-10-乙酸基-10,11-二氫-5H-二苯[b,f]吖庚因-5-甲酰胺;;EslicarbazepineAcetate; [(5S)-11-carbamoyl-5,6-dihydrobenzo[b][1]benzazepin-5-yl] acetate; Exalief; Eslicarbazepineacetate; S-(?)-10-

貨號	規格	價格	上海	北京	武漢	南京
S81439-10mg	99.2%	￥180.00 S81439-10mg ￥180.00 現貨	8 8	-	-	-
S81439-50mg	99.2%	￥280.00 S81439-50mg ￥280.00 現貨	3 3	-	-	-
S81439-100mg	99.2%	￥480.00 S81439-100mg ￥480.00 現貨	12 >10	-	-	-
S81439-1g	99.2%	￥1800.00 S81439-1g ￥1800.00 現貨	7 7	-	-	-

產品介紹

Eslicarbazepine acetate (BIA 2-093), an antiepileptic drug, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.

產品描述：

Eslicarbazepine acetate (BIA 2-093), an antiepileptic drug, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.

靶點：

Beta-secretase;Sodium Channel;Beta-Secretase;?SodiumChannel

體內研究：

Eslicarbazepine acetate is an antiepileptic drug. It is a prodrug which is activated to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine. Eslicarbazepine acetate is a prodrug for (S)-(+)-licarbazepine, the major active metabolite of oxcarbazepine. Its mechanism of action is therefore identical to that of oxcarbazepine. Eslicarbazepine acetate may not produce as high peak levels of (S)-(+)-licarbazepine immediately after dosing as does oxcarbazepine which could theoretically improve tolerability

參考文獻：

1. Sibhghatulla Shaikh, et al. Aptiom (Eslicarbazepine Acetate) as a Dual Inhibitor of β-Secretase and Voltage-Gated Sodium Channel: Advancement in Alzheimer's Disease-Epilepsy Linkage via an Enzoinformatics Study. CNS & Neurological Disorders Drug Targets Volume 13 , Issue 7 , 2014.

溶解性：

DMSO : ≥ 100 mg/mL (337.47 mM)

保存條件：

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	3.375 ml	16.873 ml	33.747 ml
5 mM	0.675 ml	3.375 ml	6.749 ml
10 mM	0.337 ml	1.687 ml	3.375 ml
50 mM	0.067 ml	0.337 ml	0.675 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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