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Sertaconazole Nitrate

    
≥98%

Sertaconazole Nitrate

源葉(MedMol)
S81183 一鍵復(fù)制產(chǎn)品信息
99592-39-9
C20H16Cl3N3O4S
500.78
硝酸舍他康唑; 1-(2-((7-氯苯并(b)噻吩-3-基)甲氧基)-2-(2,4-二氯苯基)乙基)-1H-咪唑硝酸鹽
貨號 規(guī)格 價(jià)格 上海 北京 武漢 南京 購買數(shù)量
S81183-10mg
≥98% ¥170.00 >10 - - -
S81183-50mg
≥98% ¥640.00 >10 - - -
S81183-250mg
≥98% ¥2300.00 >10 - - -
S81183-500mg
≥98% ¥3500.00 >10 - - -
S81183-1g
≥98% ¥6000.00 >10 - - -
產(chǎn)品介紹 參考文獻(xiàn) 質(zhì)檢證書(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

Sertaconazole nitrate (FI7056) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole nitrate is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy, and can also inhibit the migration of cells

產(chǎn)品描述: Sertaconazole nitrate (FI7056) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole nitrate is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy, and can also inhibit the migration of cells
靶點(diǎn): Fungal;Autophagy;Apoptosis;p38 MAPK;Microtubule/Tubulin;Antibiotic;?Antifungal
體內(nèi)研究: Sertaconazole nitrate (1% (w/v); apply to the left ear, once) suppresses of TPA-induced ear edema CD-1 mice
參考文獻(xiàn): 1. Carrillo-Mu?oz AJ, et al. In-vitro antifungal activity of sertaconazole, econazole, and bifonazole against Candida spp. J Antimicrob Chemother. 1995 Oct;36(4):713-6. 2. Sur R, et al. Anti-inflammatory activity of sertaconazole nitrate is mediated via activation of a p38-COX-2-PGE2 pathway. J Invest Dermatol. 2008 Feb;128(2):336-44. 3. Sebastian J, et al. Sertaconazole induced toxicity in HeLa cells through mitotic arrest and inhibition of microtubule assembly. Naunyn Schmiedebergs Arch Pharmacol. 2021 Jun;394(6):1231-1249. 4. Zhang W, et al. Sertaconazole provokes proapoptotic autophagy via stabilizing TRADD in nonsmall cell lung cancer cells. MedComm (2020). 2021 Dec 16;2(4):821-837.
溶解性: Soluble  in  DMSO
保存條件: 2-8℃
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 1.997 ml 9.984 ml 19.969 ml
5 mM 0.399 ml 1.997 ml 3.994 ml
10 mM 0.2 ml 0.998 ml 1.997 ml
50 mM 0.04 ml 0.2 ml 0.399 ml
注意: 部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。

參考文獻(xiàn)

質(zhì)檢證書(COA)

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請輸入貨號和一個(gè)與之匹配的批號。
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批號:JS298415 貨號:S20001-25g
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摩爾濃度計(jì)算器

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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