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Fluvastatin

99.9%

Fluvastatin

質檢下載產品說明書核磁下載

品牌：源葉(MedMol)

產品編號：S81136 一鍵復制產品信息

CAS號：93957-54-1

分子式：C₂₄H₂₆FNO₄

分子量：411.47

別名：氟伐他汀;7-[3-(4-氟苯基)-1-(1-甲基乙基)-1H-吲哚-2-基]-3,5-二羥基-6-庚烯酸

貨號	規格	價格	上海	北京	武漢	南京
S81136-10mg	99.9%	￥230.00 S81136-10mg ￥230.00 現貨	7 7	-	-	-
S81136-50mg	99.9%	￥610.00 S81136-50mg ￥610.00 現貨	5 5	-	-	-
S81136-100mg	99.9%	￥930.00 S81136-100mg ￥930.00 現貨	1 1	-	-	-

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產品介紹參考文獻質檢證書(COA) 摩爾濃度計算器相關產品

產品介紹

Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway

產品描述：

靶點：

IC50: 8 nM (HMG-CoA reductase);HMG-CoAReductase

參考文獻：

1. Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24. [Epub ahead of print] 2. Makabe S, Takahashi Y, Watanabe H, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84. 3. Zhang W, Wu J, Zhou L, et al. Fluvastatin, a lipophilic statin, induces apoptosis in human hepatocellular carcinoma cells through mitochondria-operated pathway. Indian J Exp Biol. 2010 Dec;48(12):1167-74. 4. Scripture CD, Pieper JA. Clinical pharmacokinetics of fluvastatin. Clin Pharmacokinet. 2001;40(4):263-81.

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	2.43 ml	12.152 ml	24.303 ml
5 mM	0.486 ml	2.43 ml	4.861 ml
10 mM	0.243 ml	1.215 ml	2.43 ml
50 mM	0.049 ml	0.243 ml	0.486 ml