貨號	規格	價格	上海	北京	武漢	南京
S81089-5mg	99.1%	￥100.00 S81089-5mg ￥100.00 現貨	16 >10	-	-	-
S81089-10mg	99.1%	￥168.00 S81089-10mg ￥168.00 現貨	2 2	-	-	-
S81089-50mg	99.1%	￥570.00 S81089-50mg ￥570.00 現貨	2 2	-	-	-
S81089-250mg	≥99%	￥1450.00 S81089-250mg ￥1450.00 2-3天	0 貨期：2-3天	-	-	-

產品介紹

Atosiban (RW22164; RWJ22164) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research

產品描述：

靶點：

Oxytocin Receptor;Vasopressin Receptor;OxytocinReceptor;?VasopressinReceptor

體內研究：

The posterior pituitary hormones, oxytocin and arginine vasopressin, differ in structure by only two amino acids, and Atosiban influences physiological effects of arginine vasopressin on the feto-maternal cardiovascular and renal systems. In late-gestation sheep, the administration of Atosiban for 1 hour fails to induce fetomaternal cardiovascular changes. Atosiban blocks the activation of oxytocin-receptor-expressing neurons in the parabrachial nucleus of mice.

參考文獻：

1. Sanu O, et al. Critical appraisal and clinical utility of atosiban in the management of preterm labor. Ther Clin Risk Manag. 2010 Apr 26;6:191-9. 2. Philip J Ryan, et al. Oxytocin-receptor-expressing Neurons in the Parabrachial Nucleus Regulate Fluid Intake. Nat Neurosci. 2017 Dec;20(12):1722-1733.

溶解性：

H2O : 16.67 mg/mL (16.77 mM; Need ultrasonic) DMSO : ≥ 16.67 mg/mL (16.77 mM)

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	1.006 ml	5.029 ml	10.058 ml
5 mM	0.201 ml	1.006 ml	2.012 ml
10 mM	0.101 ml	0.503 ml	1.006 ml
50 mM	0.02 ml	0.101 ml	0.201 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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