貨號	規格	價格	上海	北京	武漢	南京
S80957-50mg	≥98%	￥360.00 S80957-50mg ￥360.00 現貨	566 >10	-	-	-
S80957-100mg	99.2%	￥680.00 S80957-100mg ￥680.00 現貨	285 >10	-	-	-
S80957-500mg	≥98%	￥1800.00 S80957-500mg ￥1800.00 現貨	56 >10	-	-	-

產品介紹

Epinastine (WAL801) is an antihistamine and mast cell stabilizer. Epinastine is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine also inhibits IL-8 release and has an antiallergic action

產品描述：

靶點：

Histamine Receptor

體內研究：

Epinastine shows a high affinity to H1-receptors in receptor binding studies in the guinea pig ileum. Epinastine inhibits histamine-induced reactions in the skin or the lung of rats, dogs and guinea pigs

參考文獻：

1. Fugner, A., et al., In vitro and in vivo studies of the non-sedating antihistamine epinastine. Arzneimittelforschung, 1988. 38(10): p. 1446-53. 2. Roeder, T., J. Degen, and M. Gewecke, Epinastine, a highly specific antagonist of insect neuronal octopamine receptors. Eur J Pharmacol, 1998. 349(2-3): p. 171-7. 3. Kamei, C., et al., Antiallergic effect of epinastine (WAL 801 CL) on immediate hypersensitivity reactions: (I). Elucidation of the mechanism for histamine release inhibition. Immunopharmacol Immunotoxicol, 1992. 14(1-2): p. 191-205. 4. Kohyama, T., et al., A novel antiallergic drug epinastine inhibits IL-8 release from human eosinophils. Biochem Biophys Res Commun, 1997. 230(1): p. 125-8.

溶解性：

DMSO : ≥ 50 mg/mL (200.55 mM) H2O : < 0.1 mg/mL (insoluble)

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	4.011 ml	20.055 ml	40.111 ml
5 mM	0.802 ml	4.011 ml	8.022 ml
10 mM	0.401 ml	2.006 ml	4.011 ml
50 mM	0.08 ml	0.401 ml	0.802 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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