貨號	規(guī)格	價格	上海	北京	武漢	南京	購買數(shù)量
S80653-10mg	≥99%(HPLC)	￥120.00 S80653-10mg ￥120.00 現(xiàn)貨	429 >10	-	-	-
S80653-50mg	≥99%(HPLC)	￥320.00 S80653-50mg ￥320.00 現(xiàn)貨	94 >10	-	-	-

產(chǎn)品介紹

Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis

產(chǎn)品描述：

靶點：

Amebae;Antibiotic;Parasite

體內研究：

Secnidazole (100 μL; ip.; for 5 days) has protective activity against S.marcescens pathogenesis and can diminish its pathogenesis in mice

參考文獻：

1. Secnidazole. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury, National Institute of Diabetes and Digestive and Kidney Diseases, 25 February 2020. 2. Helen S Pentikis, et al. In vitro metabolic profile and drug-drug interaction assessment of secnidazole, a high-dose 5-nitroimidazole antibiotic for the treatment of bacterial vaginosis. Pharmacol Res Perspect. 2020 Aug;8(4):e00634. 3. Ahdab N Khayyat, et al. Secnidazole Is a Promising Imidazole Mitigator of Serratia marcescens Virulence. Microorganisms. 2021 Nov 11;9(11):2333.

溶解性：

DMSO : ≥ 30 mg/mL (162.00 mM) H2O : 25 mg/mL (135.00 mM; Need ultrasonic)

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	5.4 ml	27.001 ml	54.002 ml
5 mM	1.08 ml	5.4 ml	10.8 ml
10 mM	0.54 ml	2.7 ml	5.4 ml
50 mM	0.108 ml	0.54 ml	1.08 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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分子摩爾量

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