| 產(chǎn)品描述： | Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research |
| 靶點： |
5-HT Receptor;Reactive Oxygen Species;DopamineReceptor;5-HTReceptor |
| 體內(nèi)研究： |
Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) reduces anxiety/depression behaviors. Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) restores IS-shifted β-diversity in the gut microbiota. |
| 參考文獻： |
1. Salimi A, et, al. Analysis of Toxicity Effects of Buspirone, Cetirizine and Olanzapine on Human Blood Lymphocytes: in Vitro Model. Curr Clin Pharmacol. 2018;13(2):120-127. 2. Kim JK, et, al. Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice. Sci Rep. 2021 Mar 17;11(1):6094. |
| 溶解性： |
H2O : ≥ 100 mg/mL (236.99 mM) DMSO : 50 mg/mL (118.49 mM; Need ultrasonic) |
| 保存條件： |
-20℃ |
| 配置溶液濃度參考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.37 ml |
11.849 ml |
23.699 ml |
| 5 mM |
0.474 ml |
2.37 ml |
4.74 ml |
| 10 mM |
0.237 ml |
1.185 ml |
2.37 ml |
| 50 mM |
0.047 ml |
0.237 ml |
0.474 ml |
|
| 注意： |
部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。 |
上海工商
危險品化學品經(jīng)營許可證（不帶存儲）
營業(yè)執(zhí)照(三證合一)
北京