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Difluprednate

    
99.6%

Difluprednate

源葉(MedMol)
S80559 一鍵復(fù)制產(chǎn)品信息
23674-86-4
C27H34F2O7
508.55
二氟孕甾丁酯;雙氟潑尼酯;Durezol; difluprednate; Difluprednate; UNII-S8A06QG2QE; DFBA; Myser; Difluoroprednisolone butyrate acetate; Epitopic; 6ALPHA,9ALPHA-DIFLUOROPREDNISOLONE 21-ACETATE 17-BUTYRATE;
貨號(hào) 規(guī)格 價(jià)格 上海 北京 武漢 南京 購(gòu)買數(shù)量
S80559-50mg
99.6% ¥200.00 2 - - -
S80559-100mg
99.6% ¥350.00 5 - - -
S80559-500mg
99.6% ¥1600.00 3 - - -
產(chǎn)品介紹 參考文獻(xiàn) 質(zhì)檢證書(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

Difluprednate(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.

產(chǎn)品描述: Difluprednate(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.
體內(nèi)研究: Difluprednate emulsion is rapidly deacetylated in the aqueous humor to difluoroprednisolone butyrate (DFB) in rats and rabbits, the drug's active metabolite, which has a similar corticosteroid activity profile. Radio-labeled difluprednate is instilled in the right eyes of pigmented rabbits in a separate study examining DFBA excretion. Difluprednate (0.05% emulsion) results in higher aqueous humor concentrations than the suspension form in the eyes of rabbits. Difluprednate concentrations ≥0.01% shows a statistically significant inhibition of inflammation compared to saline in a rabbit model, with the anti-inflammatory response proceeding in a dose-dependent manner. Difluprednate suppresses uveitis in all three concentration (0.002%, 0.01%, and 0.05%) in a dose-dependent manner in rats, and difluprednate 0.05% shows statistically superior anti-inflammatory activity compared to Betamethasone (0.1%).
參考文獻(xiàn): 1. Donnenfeld ED, et al. Clin Ophthalmol, 2011, 5, 811-816. 2.Jamal KN, et al. Clin Ophthalmol, 2009, 3, 381-390.
溶解性: Soluble  in  DMSO、Ethanol
保存條件: 2-8℃
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 1.966 ml 9.832 ml 19.664 ml
5 mM 0.393 ml 1.966 ml 3.933 ml
10 mM 0.197 ml 0.983 ml 1.966 ml
50 mM 0.039 ml 0.197 ml 0.393 ml
注意: 部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。

參考文獻(xiàn)

質(zhì)檢證書(COA)

如何獲取質(zhì)檢證書(COA)?
請(qǐng)輸入貨號(hào)和一個(gè)與之匹配的批號(hào)。
例如:
批號(hào):JS298415 貨號(hào):S20001-25g
在貨品標(biāo)簽上如何找到貨號(hào)和批號(hào)?

摩爾濃度計(jì)算器

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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