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ALLOPURINOL RIBOSIDE

    
≥99%

ALLOPURINOL RIBOSIDE

源葉(MedMol)
S80426 一鍵復制產品信息
16220-07-8
C10H12N4O5
268.226
1-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE-4-ONE;1-BETA-D-RIBOFURANOSYLPYRAZOLO[3,4-D]PYRIMIDIN-4-ONE;ALLOPURINOL RIBOSIDE;8-AZA-7-DEAZAINOSINE;1-β-d-ribofuranosyl-1h-pyrazolo[3,4-d]pyrimidi
貨號 規格 價格 上海 北京 武漢 南京 購買數量
S80426-5mg
≥99% ¥1200.00 貨期:2-3天 - - -
S80426-25mg
≥99% ¥3200.00 貨期:2-3天 - - -
產品介紹 參考文獻 質檢證書(COA) 摩爾濃度計算器 相關產品

產品介紹

Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites.

產品描述: Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites.
靶點: Leishmania;EndogenousMetabolite;Parasite;DrugMetabolite
體內研究: Allopurinol riboside peaks in plasma 1.6 hours after administration, has an elimination half-life of 3 hours, and steady-state concentrations in the therapeutic range. After oral administration, unexpectedly low levels of allopurinol riboside in plasma are attributable to incomplete absorption and rapid renal clearance. Probenecid reduces the renal clearance of allopurinol riboside, extends the half-life of allopurinol riboside in plasma, and triples the levels of allopurinol riboside in plasma
參考文獻: 1. Nishida Y, et al. Inhibition of purine nucleoside phosphorylase activity and of T-cell function with allopurinol-riboside. Agents Actions. 1979 Dec;9(5-6):549-52. 2. Pacher P, et al. Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev. 2006 Mar;58(1):87-114. 3. Shapiro TA, et al. Pharmacokinetics and metabolism of allopurinol riboside. Clin Pharmacol Ther. 1991 May;49(5):506-14. 4. Were JB, et al. Effects of probenecid on the pharmacokinetics of allopurinol riboside. Antimicrob Agents Chemother. 1993 May;37(5):1193-6.
溶解性: Soluble  in  DMSO
保存條件: 2-8℃
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 3.728 ml 18.641 ml 37.282 ml
5 mM 0.746 ml 3.728 ml 7.456 ml
10 mM 0.373 ml 1.864 ml 3.728 ml
50 mM 0.075 ml 0.373 ml 0.746 ml
注意: 部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。

參考文獻

質檢證書(COA)

如何獲取質檢證書(COA)?
請輸入貨號和一個與之匹配的批號。
例如:
批號:JS298415 貨號:S20001-25g
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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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