貨號	規格	價格	上海	北京	武漢	南京
S80322-5mg	98.8%	￥98.00 S80322-5mg ￥98.00 現貨	15 >10	-	-	-
S80322-1mg	98.8%	￥183.00 S80322-1mg ￥183.00 現貨	13 >10	-	-	-
S80322-25mg	≥98%	￥300.00 S80322-25mg ￥300.00 2-3天	0 貨期：2-3天	-	-	-
S80322-10mg	98.8%	￥462.00 S80322-10mg ￥462.00 現貨	7 7	-	-	-
S80322-50mg	98.8%	￥560.00 S80322-50mg ￥560.00 現貨	6 6	-	-	-
S80322-100mg	98.8%	￥900.00 S80322-100mg ￥900.00 現貨	4 4	-	-	-

大包裝詢價收藏產品

加入購物車

產品介紹

4μ8C(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.

產品描述：

4μ8C(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.

靶點：

IRE1

體內研究：

4μ8C reverses the ER stress-dependent loss of several known RIDD targets, with an EC50 of approximately 4 μM, approximating that of inhibition of XBP1 target gene activation

細胞實驗：

Cells are seeded in phenol red-free cell culture medium in 96 or 24 well dishes at a density of 5 × 103 or 5 × 104 cells per well, respectively. Cultures are incubated for 16 h before treatment with 4μ8C for 24 h. Cultures are then analyzed by the addition of 200 μM WST1 and 10 μM phenazine metho-sulfate. After development of the reagent for 2 h at 37°C, the hydrolyzed dye is detected by absorbance at 450 nm, after subtracting background and absorbance at 595 nm. Alternatively, cell viability is determined by staining of the adherent culture with crystal violet. Quantitation of the dye uptake is analyzed by extensive washing of the stained cells with water and solublization of the crystal violet in methanol followed by absorbance measurements at 595 nm. (Only for Reference)

參考文獻：

1.Cross BC, et al. Proc Natl Acad Sci U S A. 2012, 109(15), E869-878. 2.Kemp KL, et al. J Biol Chem. 2013, 288(46), 33272-33282.

溶解性：

DMSO:20.4 mg/mL (100 mM)

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	4.898 ml	24.488 ml	48.976 ml
5 mM	0.98 ml	4.898 ml	9.795 ml
10 mM	0.49 ml	2.449 ml	4.898 ml
50 mM	0.098 ml	0.49 ml	0.98 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

質檢證書(COA)

輸入產品批號：

如何獲取質檢證書(COA)?

請輸入貨號和一個與之匹配的批號。
例如:
批號：JS298415 貨號：S20001-25g
在貨品標簽上如何找到貨號和批號?

摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

質量

濃度

體積

分子摩爾量

計算重置

玖玖资源网站,爆乳久久久,日韩精品乱码久久久蜜桃,精品呦国产一区二区三区,国产伦高清一区二区三区,sese一区二区,午夜精品福利一区二区三区,三级黄色网站久久免费

8-Formyl-4-methylumbelliferone