PF-04971729(Ertugliflozin)是鈉離子依賴的葡萄糖協(xié)同轉(zhuǎn)運(yùn)蛋白2(SGLT2)抑制劑。;PF-04971729(Ertugliflozin) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2(SGLT2).Ertugliflozin (MK-8835, PF-04971729) is a potent and selective sodium-dependent glucose cotransporter 2 inhibitor with IC50 values of 0.877 nM for h-SGLT2 and 1000-fold higher for h-SGLT1.