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薯蕷皂苷元

    
分析標準品,HPLC≥98%

Diosgenin

源葉
B21177 一鍵復制產品信息
512-04-9
C27H42O3
414.61
MFCD00016887
薯蕷皂素;地奧配質
貨號 規格 價格 上海 北京 武漢 南京 購買數量
B21177-20mg
分析標準品,HPLC≥98% ¥50.00 >10 2 1 4
B21177-50mg
分析標準品,HPLC≥98% ¥110.00 >10 - - -
B21177-100mg
分析標準品,HPLC≥98% ¥180.00 >10 - - -
B21177-200mg
分析標準品,HPLC≥98% ¥300.00 >10 - - -
產品介紹 參考文獻(38篇) 質檢證書(COA) 摩爾濃度計算器 相關產品

產品介紹

藥理藥效:薯蕷皂素是一種植物類固醇,誘導結腸癌細胞凋亡和誘導骨肉瘤細胞凋亡,細胞周期阻滯和COX活性。

熔點: 205-208°C
沸點: 527.1 °C at 760 mmHg
比旋光度: D25 -129° (c = 1.4 in CHCl3)
外觀: 白色至淡黃色片狀或針狀結晶
溶解性: 二氯甲烷:5mg/ml(需超聲)
乙醇:1mg/ml(需超聲)
DMSO:基本不溶
HPLC檢測建議用二氯甲烷溶解后再用甲醇稀釋,純甲醇溶解性不好。
儲存條件: 2-8℃
注意: 部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。

參考文獻(38篇)

33. [IF=4.7] Xinyu Li et al."Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy."JOURNAL OF NEUROCHEMISTRY.2023 Dec;: 32. [IF=7.3] Rui-Fang Dong et al."Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer therapy."BRITISH JOURNAL OF PHARMACOLOGY.2023 Jun;: 31. [IF=5.195] Suwen Chen et al."Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic FXR-SHP-SREBP1C/PPARα/CD36 pathway."EUROPEAN JOURNAL OF PHARMACOLOGY.2023 Aug;952:175808 30. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199 29. [IF=6.525] Lixia Chen et al."A Novel Diosgenin-Based Liposome Delivery System Combined with Doxorubicin for Liver Cancer Therapy."Pharmaceutics.2022 Aug;14(8):1685 28. [IF=6.417] Chen Zhou et al."22R- but not 22S-hydroxycholesterol is recruited for diosgenin biosynthesis."Plant Journal. 2021 Dec 07 27. [IF=5.753] Jianghong Gao et al."Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum.."Front Plant Sci. 2021 Dec;12:809579-809579 26. [IF=3.645] Shuo Gu et al."Develop a stepwise integrated method to screen biomarkers of Baihe-Dihuang Tang on the treatment of depression in rats applying with composition screened, untargeted, and targeted metabolomics analysis."Journal Of Separation Science. 2022 M 25. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150 24. [IF=3.998] Chengfei Zhang et al."Transcriptome analysis of the effect of diosgenin on autoimmune thyroiditis in a rat model."Sci Rep-Uk. 2021 Mar;11(1):1-12 23. [IF=4.242] Shun Zhou et al."Anthelmintic efficacy of 35 herbal medicines against a monogenean parasite, Gyrodactylus kobayashii, infecting goldfish (Carassius auratus)."Aquaculture. 2020 May;521:734992 22. [IF=5.275] Liangqun Li et al."Microbial transformation of diosgenin to diosgenone by Wickerhamomyces anomalus JQ-1 obtained from Naxi traditional Jiu Qu."Bioorg Chem. 2020 Jan;95:103508 21. [IF=5.923] Lixiu Hou et al."Genome-Wide Identification of CYP72A Gene Family and Expression Patterns Related to Jasmonic Acid Treatment and Steroidal Saponin Accumulation in Dioscorea zingiberensis."Int J Mol Sci. 2021 Jan;22(20):10953 20. [IF=0.533] P Wang et al."Ionic Liquid-Based Ultrasonic/Microwave-Assisted Extraction of Steroidal Saponins from Dioscorea zingiberensis C. H. Wright."Trop J Pharm Res. 2014 Sep;13(8):1339-1345 19. [IF=2.998] Lei Lei et al."Preparation of diosgenin from Dioscorea zingiberensis C. H. Wright by stepwise biocatalysis-foam separation-preparative high-performance liquid chromatography (P-HPLC)."Eur Food Res Technol. 2018 Aug;244(8):1447-1452 18. [IF=4.759] Mengshun Liu et al."Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides."J Chromatogr A. 2014 Nov;1368:116 17. [IF=5.64] Wu Dousheng et al."Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum."Front Microbiol. 2015 Dec;0:1466 16. [IF=9.297] Peng Wang et al."Conversion of steroid saponins into diosgenin by catalytic hydrolysis using acid-functionalized ionic liquid under microwave irradiation."J Clean Prod. 2014 Sep;79:265 15. Wang, Peng, et al. "Conversion of steroid saponins into diosgenin by catalytic hydrolysis using acid-functionalized ionic liquid under microwave irradiation." Journal of cleaner production 79 (2014): 265-270.https://doi.org/10.1016/j.jclepro.2014.05.041 14. 李慧敏,鄭淘,曾藝瓊,范郁冰,李衛真,嚴建業,趙利平,鄭慧,楊勇.AHP-CRITIC權重分析法綜合優選玉竹全粉改性工藝[J].食品與發酵工業,2021,47(05):138-146. 13. 胡佳莉. 紅曲黃精發酵工藝及免疫調節和降血脂作用研究[D].廣東藥科大學,2020. 12. 周曉,李婧琳,鄒俊波,張小飛,郭東艷,程江雪,史亞軍,石心紅,賈曉斌.粒子設計對參苓白術散在大鼠體內藥動學過程的影響[J].中草藥,2020,51(19):4925-4933. 11. 石鴻輝 苑廣偉 廖正睿 等. 不同菌種發酵對辣木莖葉粉的營養價值及其抗氧化活性的影響[J]. 食品工業科技 2019 040(009):91-97 104. 10. 張澤銳, 黃申, 劉京晶,等. 多花黃精和長梗黃精花主要營養功效成分[J]. 中國中藥雜志, 2020, v.45(06):123-127. 9. 楊亞利 劉佳 張鵬 等. 4種重樓不同部位薯蕷皂苷及皂苷元含量的分析[J]. 時珍國醫國藥 2016(5):1035-1038. 8. 胡佳莉, 劉林, 李鐘,等. 黃精發酵過程中有效成分含量與色澤的相關性[J]. 中國實驗方劑學雜志, 2020(15). 7. 陳振興,趙瑞芝.薯蕷皂苷元對鹽酸米托蒽醌誘導耐藥子宮肉瘤細胞MES-SA/MX2凋亡的增敏作用[J].中國藥學雜志,2017,52(24):2157-2160. 6. 孫蕊, 牛潔, 曹芳,等. 薯蕷皂苷元對LPS誘導的人胚肺成纖維細胞的干預機制研究[J]. 環球中醫藥, 2019, 012(007):988-993. 5. 趙楊, 曾禾鑫, 成志強,等. 鹽蒺藜的制備及質量控制研究[J]. 時珍國醫國藥, 2019, v.30;No.288(08):98-100. 4. 李會, 張佳佳, 梁靜怡,等. 基于酶法輔提和微波酸解的黃姜薯蕷皂苷元清潔生產工藝[J]. 食品科學, 2012, 033(020):94-98. 3. 袁志鷹, 羅林明, 陳乃宏,等. 基于UPLC-Q-TOF-MS法分析百合珠芽化學成分及其薯蕷皂苷元抗腫瘤活性研究[J]. 天然產物研究與開發, 2019, 31(05):808-813. 2. 楊南南 李會 吳燕 張曉梅 許正宏 史勁松.Gibberella intermedia WX12產特異性糖苷酶的發酵工藝優化[J].食品與生物技術學報 2016 35(10):1028-1034. 1. 趙麗蓉 羅漢 相英龍 等. Box-Benhken響應面法優化微波提取黃精總皂苷的條件[J]. 中國現代中藥 2018 20(008):1010-1015.

質檢證書(COA)

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請輸入貨號和一個與之匹配的批號。
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批號:JS298415 貨號:S20001-25g
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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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